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New Drug: Amivantamab for EGFR Exon 20 Insertion Mutant NSCLC post-platinum

New Drug: Amivantamab for EGFR Exon 20 Insertion Mutant NSCLC post-platinum
Study:
  • Single-arm phase II study (CHRYSALIS)
  • Advanced/metastatic NSCLC (EGFR Exon20ins) second-line post-platinum chemo
  • Amivantamab single agent
Efficacy:
  • ORR: 36% [25%-47%]
  • Median DoR: 6.8 mos [5.0 mos – NR]
  • Median PFS: 8.3 mos [5.5 – 12.7 mos]
  • Median OS: 22.8 mos [14.0 mos – NR]
Safety:
  • Grade >=3 AEs: Rash (3%), infusion related reaction (2%)

J Thor Oncol 2021;16(3): s108

Sabari JK, et al. Amivantamab in Post-platinum EGFR Exon 20 Insertion Mutant Non-Small Cell Lung Cancer

https://doi.org/10.1016/j.jtho.2021.01.284

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Altai Chemo Planner employs Altai Protocol Library that includes over 1000 chemotherapy protocols for both Hematology and Oncology. You can find major guidelines' protocols, parenteral, and oral, in the library. Altai Protocol Library is frequently and regularly updated.

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