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New Drug: endometrial cancer - Altai Oncology

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New Drug: Dostarlimab-gxly for dMMR endometrial cancer

New Drug: Dostarlimab-gxly for dMMR endometrial cancer
  • Multicenter, multicohort, open-abel trial (GARNET)
  • dMMR recurrent or advanced endometrial cancer who had progressed on or after a platinum-containing regimen
  • Dostarlimab-gxly q21 (n=141)
  • ORR: 45.4% [37.0-54.0]; CR: 15.6%; PR:29.8%
  • 12 mos DOR: 85.9%
  • 24 mos DOR: 54.7%
  • Any grade AEs: Asthenia (40%), diarrhea (25%), anemia (25%), neutropenia (12%), skin rash (14%).

BMJ 2022, 10 (1)

Oaknin A et al. ¨Clinical activity and safety of the anti-PD-1 monoclonal antibody dostarlimab for patients with recurrent or advanced dMMR endometrial cancer l ¨


Reviewed by Elvin CHALABİYEV, MD on FEB 24, 2023

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Altai Chemo Planner employs Altai Protocol Library that includes over 1000 chemotherapy protocols for both Hematology and Oncology. You can find major guidelines' protocols, parenteral, and oral, in the library. Altai Protocol Library is frequently and regularly updated.

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