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New Drug: Glofitamab-gxbm for selected relapsed or refractory large B-cell lymphomas

New Drug: Glofitamab-gxbm for selected relapsed or refractory large B-cell lymphomas
Study:
  • Phase I-II, open-label, multicenter study
  • Relapse or refractory large cell lymphoma
  • Glofitamab (n=132)
Efficacy:
  • cORR: 56% [74 of 132 pts]
  • CR: 43% [ 56 of 132 pts]
  • mDoR: 18.4 mos [11.4-NR]
Safety:
  • Grade≥3: CRS (4.3%), ICANS (4.8%)

https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/761309s000lbl.pdf

Reviewed by Elvin CHALABİYEV, MD on AUG 10, 2023

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