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New Drug: Oral relugolix for androgen-deprivation therapy in advanced prostate cancer

New Drug: Oral relugolix for androgen-deprivation therapy in advanced prostate cancer

Open-label, phase 3 trial
Candidates for >=1 yr of continuous androgen-deprivation therapy
Oral Relugolix (n=622) vs. leuprolide (n=308)
Sustained testosterone suppression: 96.7% vs. 88.8% (non-inferior)
Probability of castration on day 4: 56% vs. 0%
PSA response on day 15: 79.4% vs. 19.8%
Grade 3-4 AEs: 18.0% vs. 20.5%

N Engl J Med 2020;382:2187-96.
Shore ND, et al. Oral Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer
https://doi.org/10.1056/NEJMoa2004325

Reviewed by Ulas Darda Bayraktar, MD on Dec 22, 2020

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Altai Chemo Planner employs Altai Protocol Library that includes over 1000 chemotherapy protocols for both Hematology and Oncology. You can find major guidelines' protocols, parenteral, and oral, in the library. Altai Protocol Library is frequently and regularly updated.

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