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New Drug: Tisotumab vedotin for advanced cervical cancer

New Drug: Tisotumab vedotin for advanced cervical cancer
Study:
  • Open-label, single-arm Phase II trial (innovaTV 204)
  • Recurrent/metastatic squamous cell, adenoCa or adenosquamous cervical cancer, progressed on/after doublet chemo
  • Tisotumab vedotin 2 mg/kg (max 200 mg) q21 (N=102)
Efficacy:
  • ORR: 24% [16%-33%]
  • Median DoR: 8.3 mos
Safety:
  • Grade >= 3 AEs: Neutropenia (3%), ulcerative keratitis (2%), peripheral neuropathy (2%)

Lancet Oncol. 2021;22:609.

Coleman RL, et al. Efficacy and safety of tisotumab vedotin in previously treated recurrent or metastatic cervical cancer (innovaTV 204/GOG-3023/ENGOT-cx6): a multicentre, open-label, single-arm, phase 2 study

https://doi.org/10.1016/S1470-2045(21)00056-5

Altai Chemo Planner

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Altai Chemo Planner employs Altai Protocol Library that includes over 1000 chemotherapy protocols for both Hematology and Oncology. You can find major guidelines' protocols, parenteral, and oral, in the library. Altai Protocol Library is frequently and regularly updated.

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