Altai Protocol Library

1041 protocols and counting

All protocols with references and links

All protocols reviewed by a Medical Oncologist/Hematologist

All protocols in major guidelines included

Ability to create your own protocols

Search Library Posts Search

New Indication: Adjuvant nivolumab for esophageal / GEJ cancer

New Indication: Adjuvant nivolumab for esophageal / GEJ cancer
  • Randomized, double-blind, placebo controlled phase III (CheckMate 577)
  • Resected stage II/III esophageal or gastroesophageal junction cancer (R0) who had received neoadjuvant chemoradiotherapy and NOT achieved pathological CR
  • Adjuvant nivolumab (n=532) vs. placebo (n=262)
  • Median DFS: 22.4 mos vs. 11.0 mos (HR: 0.69 [0.56-0.86])
  • DFS benefit observed regardless of histologic type and in PD-L1 negative tumors
  • Median distant metastasis-free survival: 28.3 mos vs. 17.6 mos (HR: 0.74 [0.60-0.92])
  • Grade >=3 AEs: diarrhea (<1% vs. <1%), rash (<1% vs. <1%), arthralgia (<1% vs. 0), increase in AST (<1% vs. 0)

N Engl J Med 2021;384:1191-203

Kelly RJ, et al. Adjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer

Altai Chemo Planner

Quickly Prepare Accurate Chemotherapy Orders

Altai Chemo Planner employs Altai Protocol Library that includes over 1000 chemotherapy protocols for both Hematology and Oncology. You can find major guidelines' protocols, parenteral, and oral, in the library. Altai Protocol Library is frequently and regularly updated.

Learn More