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New Indication: Atezolizumab for early-stage NSCLC - Altai Oncology

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Altai Protocol Library October 4, 2021

New Indication: Atezolizumab for early-stage NSCLC

New Indication: Atezolizumab for early-stage NSCLC
Study:	Open-label Phase III trial (IMpower010) Completely resected early-stage NSCLC s/p adjuvant platinum-based chemo Atezolizumab 1200 q21 x 1 yr vs. best supportive care
Efficacy:	Among pts with stage II-IIIA & PD-L1 >= 1% => 3-year DFS: 60.0% vs. 48.2% (HR: 0.66 [0.50-0.88]) Among all pts with stage II-IIIA => 3-yr DFS: 55.7% vs. 49.4% (HR: 0.79 [0.64-0.96])
Safety:	Grade >=3 AEs: All (21.8% vs. 11.5%)
Lancet. Published Online on Sep 20, 2021 Felip E, et al. Adjuvant atezolizumab after adjuvant chemotherapy in resected stage IB–IIIA non-small-cell lung cancer (IMpower010): a randomised, multicentre, open-label, phase 3 trial https://doi.org/10.1016/S0140-6736(21)02098-5

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Altai Chemo Planner employs Altai Protocol Library that includes over 1000 chemotherapy protocols for both Hematology and Oncology. You can find major guidelines' protocols, parenteral, and oral, in the library. Altai Protocol Library is frequently and regularly updated.