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New Indication: Axitinib for unresectable recurrent or metastatic head and neck cancer

New Indication: Axitinib for unresectable recurrent or metastatic head and neck cancer
Study:
  • Single-arm phase 2 trial
  • Unresectable recurrent or metastatic (R/M) head and neck squamous cell carcinoma (n=29)
  • 61% had at least 1 previous systemic treatment
Efficacy:
  • Median OS: 9.8 mos. 6-month OS: 70%
  • ORR: 42% => ORR higher in those with PI3K pathway alterations (75% vs. 17%)

Cancer. Online first 2020 Oct 20.

Swiecicki PL, et al. Efficacy of axitinib in metastatic head and neck cancer with novel radiographic response criteria.

https://doi.org/10.1002/cncr.33226

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Altai Chemo Planner employs Altai Protocol Library that includes over 1000 chemotherapy protocols for both Hematology and Oncology. You can find major guidelines' protocols, parenteral, and oral, in the library. Altai Protocol Library is frequently and regularly updated.

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