Altai Protocol Library

1023 protocols and counting

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All protocols reviewed by a Medical Oncologist/Hematologist

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Altai Protocol Library January 12, 2021

New Indication: Larotrectinib for TRK + Sarcomas

New Indication: Larotrectinib for TRK + Sarcomas
Study:	Analysis of three separate clinical trials Adult pts with sarcomas harboring NTRK gene fusions N = 25 => 19 soft tissue sarcoma (STS) – 4 GIST – 2 bone sarcoma (BOS)
Efficacy:	ORR: 72% => 68% (STS), 100% (GIST), 50% (BOS) CR: 16% => 16% (STS), 25% (GIST), none (BOS) Median DoR: Not-reached Median PFS: 28.3 mos [6.8 – NE]
Safety:	Grade 3 AEs: Abdominal pain (1), fatigue (1), anemia (2), anxiety (1), UTI (1)
Connective Tissue Oncology Society (CTOS) 2020 Virtual Meeting Kummar S, et al. Larotrectinib efficacy and safety in adult patients with TRK fusion sarcomas. CTOS poster

Altai Chemo Planner

Quickly Prepare Accurate Chemotherapy Orders

Altai Chemo Planner employs Altai Protocol Library that includes over 1000 chemotherapy protocols for both Hematology and Oncology. You can find major guidelines' protocols, parenteral, and oral, in the library. Altai Protocol Library is frequently and regularly updated.